酵母基因组中的低的基因复制速率

最新的Science报道，用新的方法计算酵母基因组基因的复制速率，得到的结果比用传统分子钟方法小2个数量级。

  The gene duplication rate in the yeast genome is estimated without assuming the molecular clock model to be 0.01 to 0.06 per gene per billion years; this rate is two orders of magnitude lower than a previous estimate based on the molecular clock model. This difference is explained by extensive concerted evolution via gene conversion between duplicated genes, which violates the assumption of the molecular clock in the analyses of duplicated genes. The average length of the period of concerted evolution and the gene conversion rate are estimated to be 25 million years and 28 times the mutation rate, respectively.

参考文献：
Li-zhi Gao and Hideki Innan*.
Very Low Gene Duplication Rate in the Yeast Genome.
Science, Vol 306, Issue 5700, 1367-1370 , 19 November 2004
http://www.sciencemag.org/cgi/content/abstract/306/5700/1367
http://www.sciencemag.org/cgi/content/full/306/5700/1367