the advantage of such binding for SSB activity?

1) Okazaki fragment

2) Holliday junction

3) proofreading

4) splice

5) transposition

1. Describe the different proteins during the replication and what their functions are.

3. Describe the differences between Holliday model and DSB model.

Group 10

1) Okazaki fragment

2) ORC

3) replication fork

4) transposition

1. Describe the differences between DNA and RNA?

2. Identify the major steps of homologous recombination and tell the differences between the

Holliday and the DSB repair model.

3. List the functions of sliding clamp loaders.

Group 11

1) Replicator

2) initiator

3) replisome

4) Histone

5) Holliday junction

6) replication fork

7) sliding clamp

8) Okazaki fragment

9) telomerase

10) Polymerase switching：the process of replacing DNA Pola/primase with DNA Pold or DNA

Pole

11) autonomous transposon

1. What are the functions of ssb during DNA replication?

2. How do the polymerase finish proofreading process?

3. Compare the holliday junction model with DSB model, Tell the differences between them.

4. How is the DNA unwound at the replication fork? What effect does this have on the DNA

upstream of the fork, and how does the cell deal with this effect?

5. How are sliding clamps able to get on and off the DNA?

Group 12

1) strand invasion

2) resolution

3) replication fork

4) Okazaki fragment

5) RecBCD pathway

6) mutation

1. How does DNA polymerase ensure that the correct base is added to the growing polynucleotide

chain during replication?

2. What's the function of "joint molecule"?

3. How to distinguish the "splice" and the "patch" products from the Holliday cleavage?

4. What happens to the heteroduplex after homologous recombination?

Group14

Definition: 1. processivity 2. Okazaki fragment

3. End replication problem 4 SOS response

Answering question

1. Briefly summarize the palm, thumb and finger domain of DNA polymerase and explain how

do they contribute to replication, and what’s the role of the mental ions in the palm’s activity?

2. Sliding clamps are topologically closed rings that can encircle the DNA double helix, but how

then are they able to get on and off the DNA? What purpose is served by this striking

topology?

3. If replication errors escape proofreading, what will the cell do? And explain the pathway.

4. How many models for homologous recombination? What are they? And explain the difference

between them.

Group 15

Definition: 1 phase variation 2.site-sepecific recombination

Answering: how does lambda phage promote the integration and excision of its genome into the

host cell chromosome?

Group 16

Definition: 1.DNA topoisomers 2. pseudogenes 3. Okazaki fragments 4. DSB repair pathway 5.chi

site 6. polymerase switching

Answering:

1. Why is hydrogen bonding important for the specificity of base pairing.

2. What are the main enzymes that effect the eukaryotic DNA replication

3. what are the steps of the Holliday junction.